Analysis of the relationship between liver regeneration rate and blood levels

Objectives: The aim of this study was to investigate the difference of liver function changes according to the liver regeneration rate after liver transplantation through blood tests.

Methods: Fifty donors, who underwent computed tomography (CT) 3D volumetry, were analyzed before and after liver transplantation. CT 3D volumetry was used as a study method to measure the mean liver regeneration volume and regeneration rate. Then, blood levels were measured including alanine transaminase (ALT), aminotransferase (AST), gamma-glutamyl transpeptidase (GGT) and total bilirubin.

Results: The liver regeneration rate rapidly increased from 39.13±4.91% befoone1 month and 90.31±13.09% 16 months after surgery furthermore. Blood levels rapidly increased 7 days after surgery and then decreased 16 months after surgery compared to the state before surgery.

Conclusion: This study results could be used as a basis for the prognosis of future liver transplantations.