BUCCAL EPITHELIUM REACTIVITY INDICATORS AS MARKERS OF MORPHOLOGICAL AND FUNCTIONAL IMPAIRMENT IN PATIENTS WITH DENTOALVEOLAR PATHOLOGY

Laboratory and diagnostic methods were used to perform quantitative assessment of natural microbial colonization in buccal epithelium in children (adolescents) aged 10-15 years with an optimal functional occlusion and malocclusion, and resistance of their buccal epithelial cells to artificial microbial colonization was studied as well. It was found that patients with dentoalveolar abnormalities characterized with morphological and functional disorders of varying degrees, showed dysbiotic changes in the mucosal epithelium, reflecting the severity of destabilizing processes in the oral homeostasis, and selective decrement in colonization resistance of mucous membranes due to the changes in the adhesive properties of the epithelium.