DIAGNOSIS IMMUNOPATOLOGICHESKIH DISORDERS IN CHILDREN WITH DIABETES TYPE I

According to the results of immunological, biochemical studies of blood serum and oral fluid in 92 children with autoimmune diabetes mellitus in the period of the mixed occlusion investigated the cellular, humoral links of immunity and established the balance of bone metabolism at various stages of compensation endocrinopathy. Data were compared with similar parameters 48 children of I–II health groups. The obtained results allow asserting that with increasing severity of disease in children with autoimmune diabetes mellitus there is a significant weakening of the recovery processes of bone tissue, the development of local immunodeficiency, depression of cellular immunity in the presence of pronounced immunometabolic disorders.