Study of Factors Influencing the Intestinal Microbiota in Children from 0 to 3 Months at the Mother and Child Hospital of Bingerville, Ivory Coast during 2023

Study of Factors Influencing the Intestinal Microbiota in Children from 0 to 3 Months at the Mother and Child Hospital of Bingerville, Ivory Coast during 2023 Grace Kemsol Miedjim Gbonon Mbengue Valérie Akaffou Adja Evelyne Ndôh Ngrabé Nodje- Assal Ndri Kouamé Mathias Guede Cataud Marius Assohoun Egomli Stanislas Marcelle Money Ettien Franck Djéda Gnahoré Ambroise Kouamé Kintossou Kouamé Clarisse Kangah Tatiana Afran Sidjè Arlette Diplo Flore Setchi Luc Olivier Koffi Stéphane Dosso Mireille

Introduction: Every human being builds a symbiosis with a diverse ecosystem of microorganisms: the intestinal microbiota. Its establishment, maturity, and composition evolving throughout life are dynamic processes influenced during their establishment by various factors such as gestational age, birth and feeding modalities, environment, and antibiotic use. The aim of this article is to identify the epidemiological characteristics (factors influencing the establishment and development of the intestinal microbiota) of populations of children from 0 to 3 months studied at the Mother and Child Hospital of Bingerville. Methods: A longitudinal and prospective birth cohort of populations of children from Day 0 to Month 3 was conducted. Epidemiological data were collected from the mother after signing the informed consent form. Data collection tools included the survey form, information sheet, and informed consent form. Statistical analyses were performed using XLSTAT software version 2018. Chi-square test (significance test) was used on variables such as sex and gestational age, mode of delivery, gestational age and birth mode, and birth weight. Results: A total of 52 infants were included. The socio-demographic and clinical characteristics of these newborns and their mothers were examined. Analysis of birth weight distribution according to mode of delivery and feeding mode did not reveal any significant association. Each studied characteristic was then discussed. Conclusion: The objective of the study has been achieved. However, further research is needed to obtain more generalizable results.
06 04 2024 83 92 10.9734/jalsi/2024/v27i3649 https://journaljalsi.com/index.php/JALSI/article/view/649 https://journaljalsi.com/index.php/JALSI/article/download/649/1296 https://journaljalsi.com/index.php/JALSI/article/download/649/1296 https://journaljalsi.com/index.php/JALSI/article/download/649/1297