Clinical Trial of Medicinal Synthetic Aluminum-Magnesium Silicate (Antivirt®) on Viral Loads and CD4-Lymphocytes Counts of HIV/AIDS Patients

Ezeibe, Maduike C. O. and Aleeyu, Dahiru and Ogbonna, Ijeoma J. and Kalu, Ekenma (2016) Clinical Trial of Medicinal Synthetic Aluminum-Magnesium Silicate (Antivirt®) on Viral Loads and CD4-Lymphocytes Counts of HIV/AIDS Patients. World Journal of AIDS, 06 (02). pp. 37-41. ISSN 2160-8814

[thumbnail of WJA_2016042217172086.pdf] Text
WJA_2016042217172086.pdf - Published Version

Download (279kB)

Abstract

For clinical trial of Medicinal synthetic Aluminum-magnesium silicate (MSAMS, Antivirt®), on viral loads and CD4-lymphocytes counts of HIV/AIDS patients, 10 volunteers were treated. Their blood samples were tested for viral loads and for CD4-lymphocytes counts, before the treatment and every 4 weeks during the medication. The regimen was: MSAMS (50 mg/kg), MSAMS-stabilized Ampicillin trihydrate (7.5 mg/kg) and immunace extra protection® (1 tablet/day), for 4 weeks. Then, it was reduced to 50 mg/kg (MSAMS) and the immune stimulant. When their viral loads become undetectable, they would be treated for additional 4 weeks. Initially, the Antivirt®-regimen appeared to worsen both HIV infection-load and immune deficiency but later relieved them. Patients’ mean-viral load increased (P = 0.020), from 1820.30 ± 868.75 to 2855.90 ± 960.98, after 4 weeks before reducing (P = 0.030) to 1565.20 ± 743.17, after 8 weeks. Similarly, their mean-CD4-lymphocytes count reduced (P = 0.008) from 496.80 ± 194.39 to 263.90 ± 149.26, after 4 weeks before improving (P = 0.001) to 507.90 ± 133.19, after 8 weeks.

Item Type: Article
Subjects: East India library > Medical Science
Depositing User: Unnamed user with email support@eastindialibrary.com
Date Deposited: 28 Jan 2023 08:31
Last Modified: 14 Jun 2024 12:57
URI: http://info.paperdigitallibrary.com/id/eprint/157

Actions (login required)

View Item
View Item