Wyler, Steven C. and Lord, Caleb C. and Lee, Syann and Elmquist, Joel K. and Liu, Chen (2017) Serotonergic Control of Metabolic Homeostasis. Frontiers in Cellular Neuroscience, 11. ISSN 1662-5102
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Abstract
New treatments are urgently needed to address the current epidemic of obesity and diabetes. Recent studies have highlighted multiple pathways whereby serotonin (5-HT) modulates energy homeostasis, leading to a renewed interest in the identification of 5-HT-based therapies for metabolic disease. This review aims to synthesize pharmacological and genetic studies that have found diverse functions of both central and peripheral 5-HT in the control of food intake, thermogenesis, and glucose and lipid metabolism. We also discuss the potential benefits of targeting the 5-HT system to combat metabolic disease.
Item Type: | Article |
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Subjects: | East India library > Multidisciplinary |
Depositing User: | Unnamed user with email support@eastindialibrary.com |
Date Deposited: | 06 Jun 2023 07:48 |
Last Modified: | 24 Jun 2024 05:21 |
URI: | http://info.paperdigitallibrary.com/id/eprint/1286 |