Isolation of Chemical Constituents and Invitro Antidiabetic Activity of Mirabilis Jalapa Flower Extracts

Kodical, Deepth D. and Fernandes, Jennifer and Mathew, Jane and Deepthi, K. and Bhaskar, K. Vijay (2021) Isolation of Chemical Constituents and Invitro Antidiabetic Activity of Mirabilis Jalapa Flower Extracts. Journal of Pharmaceutical Research International, 33 (60A). pp. 412-419. ISSN 2456-9119

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Official URL: https://doi.org/10.9734/jpri/2021/v33i60A34501

Abstract

Objectives: The present work was designed to investigate the phytochemical and in vitro screening of the flower extracts of Mirabilis jalapa.

Materials and Methods: Phytochemical constituents were isolated using column chromatography and characterized of the compounds were carried out using IR, 1H NMR, 13C NMR and mass spectroscopy data. In vitro anti-diabetic activity was evaluated by alpha-amylase inhibition assay and Alpha-glucosidase inhibition assay.

Results: Phytochemical investigation of the ethanol extract revealed the presence of a flavonoid Kaempferol and a triterpenoid Lupeol. In vitro investigation indicated that the Mirabilis jalapa flowers extracts has considerable anti-diabetic activity

Conclusion: The anti-diabetic activity may due to the presence of phytoconstituents like flavonoids, triterpenoids, steroids.

Item Type:	Article
Subjects:	East India library > Medical Science
Depositing User:	Unnamed user with email support@eastindialibrary.com
Date Deposited:	31 Jan 2023 08:02
Last Modified:	11 Jun 2024 13:29
URI:	http://info.paperdigitallibrary.com/id/eprint/103

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